Dana-Farber Scientists find potential loophole in pancreatic cancer defense
Dana-Farber Cancer Institute scientists and colleagues have discovered that pancreatic cancer cells' growth and spread are fueled by an unusual metabolic pathway that someday might be blocked with targeted drugs to control the deadly cancer.
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New metabolite-based diagnostic test could help detect pancreatic cancer ea
A new diagnostic test that uses a scientific technique known as metabolomic analysis may be a safe and easy screening method that could improve the prognosis of patients with pancreatic cancer through earlier detection.
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Cholesterol rafts deliver drugs inside cancer cells
DNA, siRNA and miRNA can reprogram cancer cells � that is, if these nucleic acids could cross through the cell membrane. A University of Colorado Cancer Center study published today in the journal Therapeutic Delivery shows that cholesterol "rafts" can shepherd genetic payloads into cancer cells.
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Breakthrough Prize in Life Sciences
The Lustgarten Foundation congratulates our esteemed colleague Dr. Bert Vogelstein of Johns Hopkins University, one of 11 scientists selected for the first Breakthrough Prize in Life Sciences, which recognizes excellence in research aimed at a cure for intractable diseases and extending human life. It continues to be our privilege to work with Dr. Vogelstein, a key member of our executive committee a key member of our Pancreatic Cancer Research Consortium executive committee and grant recipient, in the fight against pancreatic cancer. His dedication to advancing research, specifically for cancer genomics and tumor suppressor genes, underscores that research is the only way to beat pancreatic cancer.
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Mayo Clinic researchers identify new molecule to target in pancreatic cance
The researchers decoded a molecular pathway that is switched "on" at all times, promoting accelerated growth of pancreatic tumors, and that discovery revealed ways to disable the pathway.
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MIT researchers find new technology may enable earlier cancer diagnosis
Researchers at MIT have developed nanoparticles that can home to a tumor and interact with cancer proteins to produce thousands of biomarkers, which can then be easily detected in the patient�s urine.
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New technology allows scientists to capture and preserve cancer cells circu
Scientists report a new nanoscale Velcro-like device that captures and releases tumor cells that have broken away from primary tumors and are circulating in the bloodstream.
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Expanding the Playing Field: Immune-Based Therapy Shows Potential
Results from two early-phase clinical trials presented at the 2012 American Society of Clinical Oncology annual meeting provide further evidence that priming the immune system to attack tumors
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Minnelide gives new hope for patients with pancreatic cancer
A new drug created at the University of Minnesota shows promise for pancreatic cancer patients, according to results published today in the prestigious journal Science Translational Medicine.
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Smoking, heavy drinking linked to earlier onset of pancreatic cancer
Those who smoke and drink heavily may develop pancreatic cancer at an earlier age than those who don't, according to a study led by a University of Michigan Health System gastroenterologist.
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New Immunotherapy trials in pancreatic cancer
Researchers in NCI's Center for Cancer Research are exploring the potential of genetically engineering peripheral blood T lymphocytes to recognize and attack pancreatic cancer cells that express mesothelin.
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Testing Combination Therapy Could Reveal Clues to Biology of Pancreatic Can
A small number of patients with advanced pancreatic cancer have responded to an experimental treatment regimen in which a targeted drug is given alone and then in combination with chemotherapy.
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New treatment protocol extends survival in some cases of once inoperable pa
Investigators at the University of Texas MD Anderson Cancer Center, Houston, have reported on a new approach to treating previously inoperable complex pancreatic adenocarcinoma that has significantly increased long-term survival for some patients.
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Pancreatic Cancers Need K-ras Mutations to Survive
Researchers have shown that advanced pancreatic cancers in mice can't survive without continued expression of a mutant oncogene that "rewires" key metabolic pathways to fuel the cancer cells. These altered metabolic pathways might be potential targets for future drugs to treat the deadly cancer.
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Mayo Clinic study finds nutritional supplement works against some pancreati
The dietary supplement gamma-linolenic acid can inhibit the growth of a subset of pancreatic cancer cells and selectively promote cancer cell death in mice
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Endoscopic Ultrasound Best Detects Pancreatic Lesions Common In People At H
A team of scientists have found that more than four in 10 people considered at high risk for hereditary pancreatic cancer have small pancreatic lesions long before they have any symptoms of the deadly disease.
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Hutchinson Center scientists break through pancreas cancer treatment barrie
Research study reports extending survival in mice by 70 percent; initial studies in humans are under way
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Eating More Fiber May Reduce Pancreatic Cancer Risk
Results of a new study suggest that eating more fiber may reduce the risk of pancreatic cancer by as much as 60%. Not all types of fiber were found to provide the same protective effects, however.
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Newly identified proteins involved in pancreatic cancers
A well-known protein complex responsible for controlling how DNA is expressed plays a previously unsuspected role in preventing pancreatic cancer, according to researchers at the Stanford University School of Medicine.
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Understanding Metastasis of Pancreatic Cancers
A recent publication in Cell describes pancreatic cancer cells in an animal model begin to spread before clinically obvious tumor tissue is detected. What's more, it shows that inflammation enhances cancer progression leads to entry of cancer cells into the circulation.
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