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$5.75M grant to help researchers study role of obesity in development of pancreatic cancer

A team of researchers from the UCLA Jonsson Comprehensive Cancer Center and peer institutions has been awarded a $5.75 million grant from the National Cancer Institute to study the correlation between obesity, inflammation and pancreatic cancer. The scientists hope their findings may help people avoid getting this cancer. “We know that the biological mechanisms of […]

Chemotherapy prior to surgery may help outcomes for patients with pancreatic cancer

A clinical trial led by researchers from the University of Cincinnati has found that one-third of patients receiving chemotherapy before surgery for pancreatic cancer had very encouraging results at the time of the procedure. The results of this National Cancer Institute’s SWOG Cancer Research Network trial will be presented as part of the ASCO20 Virtual […]

Why pancreatic ductal adenocarcinoma is so lethal

Pancreatic ductal adenocarcinoma (PDA) is a deadly cancer, killing patients within a year. CSHL Professor Christopher Vakoc and his former postdoc Timothy Somerville discovered how pancreatic cells lose their identity, acquire a deadly new identity, and recruit nearby cells to help them grow, promote inflammation, and invade nearby tissues. This understanding could lead to new therapies […]

Another Step Towards Earlier Detection of Pancreatic Cancer

— Risk-prediction model uses biomarkers added to clinical and genetic risk factors A risk-prediction model combining genetic and clinical factors with circulating biomarkers can identify people at notably higher than normal risk of pancreatic cancer who could benefit from screening and early detection, a U.S. nested case-control analysis suggested. The study’s final integration of three […]

COVID-19 and Pancreatic Cancer Clinical Trials

Like every other aspect of life at this time, pancreatic cancer treatment and research has been altered by the COVID-19 pandemic. The very same scientists that work to develop better treatments and earlier detection are faced with new obstacles. This very contagious virus is affecting clinical trials and research in a number of ways. COVID-19 […]

Pancreatic cancer blocked by disrupting cellular pH balance

Scientists at Sanford Burnham Prebys have found a new way to kill pancreatic cancer cells by disrupting their pH equilibrium. The study, published in Cancer Discovery, reports how depleting an ion transport protein lowers the pH to a point that compromises pancreatic cancer cell growth. Pancreatic cancer cells–like all cancer cells–have a constant need for energy to support […]

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