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COMBAT study preliminary results show response of 32% in treatment of pancreatic tumors

Working with an international team of researchers, HonorHealth Research Institute and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, were instrumental in one of the first clinical trials showing how pancreatic cancer patients can benefit from immunotherapy, according to a four-year study published in a premier scientific journal, Nature Medicine. The […]

The first mouse model of human pancreas cancer subtypes

Scientists at Cold Spring Harbor Laboratory (CSHL) have created the first mouse model of pancreatic cancer that recreates two subtypes of the human disease. The model, published July 23, 2020 in Cancer Discovery, will help researchers investigate why some pancreatic cancers are more aggressive than others and what causes them to progress, paving the way to […]

Study suggests new potential strategy to fight against pancreatic cancer

A University of Michigan-led study is shedding new light on the way pancreatic cancer cells turn nearby connective tissue cells into co-conspirators in their deadly growth. The findings, which appear in Nature Metabolism, also suggest a new potential strategy against pancreatic cancer by identifying critical components of metabolic cross talk between cells that might be attacked […]

Ipsen scores FDA fast-track for Onivyde in first-line pancreatic cancer

The FDA designation will review the use of Onivyde (liposomal irinotecan) in combination with 5- fluorouracil/leucovorin (5-FU/LV) and oxaliplatin (OX), also known as Nalirifox, in patients with previously untreated, unresectable, locally advanced and metastatic pancreatic ductal adenocarcinoma (PDAC). The fast-track programme aids the development and also expedites the review of drugs that are designed to treat serious […]

Revealed: How cancer develops resistance to treatment

Cancer cells can turn on error-prone DNA copy pathways to adapt to cancer treatment, a breakthrough study published in the journal Science has revealed. Bacteria use the same process, termed stress-induced mutagenesis, to develop antibiotic resistance. The cells of the human body are constantly dividing, and each time need to copy a three billion-letter DNA […]

$5.75M grant to help researchers study role of obesity in development of pancreatic cancer

A team of researchers from the UCLA Jonsson Comprehensive Cancer Center and peer institutions has been awarded a $5.75 million grant from the National Cancer Institute to study the correlation between obesity, inflammation and pancreatic cancer. The scientists hope their findings may help people avoid getting this cancer. “We know that the biological mechanisms of […]

Chemotherapy prior to surgery may help outcomes for patients with pancreatic cancer

A clinical trial led by researchers from the University of Cincinnati has found that one-third of patients receiving chemotherapy before surgery for pancreatic cancer had very encouraging results at the time of the procedure. The results of this National Cancer Institute’s SWOG Cancer Research Network trial will be presented as part of the ASCO20 Virtual […]
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