World Class Research

As the largest private funder of pancreatic cancer research, we are relentlessly focused on improving patient outcomes and we are making progress every day. Thanks to separate funding to support administrative expenses, 100 percent of every donation goes directly to research.

Navigating Pancreatic Cancer

We are here to empower you to ask bold questions, seek out the best treatment options, and face the unique challenges of pancreatic cancer head-on. We want to give you the resources and information you need to make informed decisions that are best for you.

Patient Checklist

Checklist

August 1, 2018 ladmin

As overwhelming as a pancreatic cancer diagnosis is, it is important to act quickly and put a treatment plan into place. Treatment should ideally begin within one month after you receive your diagnosis. Understand your disease. Thoroughly understand what stage of pancreatic cancer you have and inquire about having your blood and tumor genetically sequenced. […]

Research

Clinical Trials Finder

July 30, 2018 ladmin

If you have been diagnosed with pancreatic cancer, a clinical trial may be your best treatment option. Many clinical trials are underway for patients in all stages of the disease and may involve new combinations of currently available drugs or new drugs that have worked in other cancers. No matter where you are in your journey, we encourage you to learn more about clinical trials.

Lets Win! Pancreatic Cancer

Let’s Win! Pancreatic Cancer

July 20, 2018 ladmin

LET’S WIN! Pancreatic Cancer A Dynamic Way to Share Information Recognizing that there is an urgent need for patients to communicate amongst themselves and with the medical community about potentially life-changing treatments and clinical trials, we are proud to be affiliated with Let’s Win. Let’s Win is an interactive online community where patients and families […]

Pancreatic Cancer Connections

July 7, 2018 ladmin

Pancreatic Cancer Connections is online social community that provides a safe space for pancreatic cancer patients and their loved ones to share their experiences, get valuable coping resources, and support one another. Patients interact with others who are facing a pancreatic cancer and can post questions to the board or message other members privately. This community forum is a valuable resource for patients, caregivers, and their loved ones to refer to at various stages of their treatment and recovery.

Patients and loved ones can sign up for Pancreatic Cancer Connections at no cost and will be welcomed into an engaging and supportive community to discuss topics including treatment options, nutrition, and coping with the disease. Pancreatic Cancer Connections is hosted by Inspire, a leading healthcare social network that connects more than 1,000,000 patients and caregivers.

Lustgarten News


Largest Match Ever #FundMoreTrials

Meet Vivian — a Stage IV pancreatic cancer patient with liver metastases who is alive today thanks to an immunotherapy clinical trial that was built upon research done through the Lustgarten Foundation and Stand Up To Cancer. She is now on a maintenance regimen to prevent a recurrence and is grateful for every day she gets to spend with her family and friends.

Stories like Vivian’s demonstrate why it is so critical that we fund as much research and as many clinical trials as possible and give other patients the chance for long-term survival. One promising multicenter trial we need to fund is PASS (Pancreatic Adenocarcinoma Signature Stratification), and we need your support. The goal is to identify medications that work best for first and second-line treatment by testing different therapies, as patients with advanced disease don’t have time to waste.

We need to ensure that as many patients as possible have the opportunity to participate in clinical trials that offer alternatives to standard of care treatments, test new therapy combinations and challenge conventional methods for treating a disease with the lowest five-year survival rate of any major cancer.

By supporting the Lustgarten Foundation, you are accelerating clinical trials that are leading to life-changing breakthroughs in pancreatic cancer treatment.

 

Learn More

Pancreatic Cancer Awareness Month

November is Pancreatic Cancer Awareness Month! Join us this month as we share inspiring stories of hope and survival, as well as generate awareness across social media to highlight the need for increased funding and research for a disease that has a 5-year survival rate only in the single digits.

This year, Thursday, November 15 will mark World Pancreatic Cancer Day, a day devoted to pancreatic cancer communities around the world. The Lustgarten Foundation, along with 70 organizations from over 30 countries and six continents, will come together to bring more attention and awareness to patients fighting this disease and their caregivers and loved ones who support them.

We invite you to take part in awareness efforts this month and show your support for pancreatic cancer patients, survivors, and their loved ones. Raising awareness can be as simple as sharing how pancreatic cancer has affected your life or someone you love and promoting awareness efforts on social media by using the appropriate hashtags.

Learn More

Holiday Rock & Roll Bash 2018

Join us for our premier fundraising event!  Every December, The Madison Square Garden Company and AMC Networks host the Holiday Rock & Roll Bash to benefit the Foundation. To date, this fabulous event has raised more than $23 million for pancreatic cancer research.
It’s a night of holiday fun – dancing, delicious food and drinks, and an exclusive performance by the world-famous Radio City Rockettes.  We gather to celebrate our success while remembering there is still much more work to be done.

This year’s event will be held on Thursday, December 13 at the exclusive TAO Downtown. Doors open at 6:30.

Information on purchasing tickets or, sponsorships and making a donation is below.

Learn More

Pancreatic Cancer News


Pancreatology Publishes Results of the PANOVA Phase 2 Pilot Trial in Advanced Pancreatic Cancer Suggesting Improved Survival of Patients Treated with Tumor Treating Fields

22. 10. 18 ladmin

-Novocure (NASDAQ: NVCR) announced today that the results of its PANOVA phase 2 pilot trial have been published in Pancreatology. The PANOVA pilot trial was a prospective, single-arm study testing the feasibility, safety and preliminary efficacy of Tumor Treating Fields in patients with advanced pancreatic cancer whose tumors could not be removed surgically and who had not received chemotherapy or radiation therapy prior to entering the clinical trial.

Ipsen Presents Real-World Pancreatic Cancer Data on ONIVYDE® at the European Society for Medical Oncology (ESMO) 2018 Annual Congress

21. 10. 18 ladmin

Ipsen Biopharmaceuticals, an affiliate of Ipsen (Euronext: IPN; ADR: IPSEY), today announced results from a retrospective, observational analysis examining the real-world dosing patterns of patients with metastatic pancreatic cancer (mPC) treated with ONIVYDE® (irinotecan liposome injection), at this year’s European Society for Medical Oncology (ESMO) annual congress taking place in Munich, Germany, Oct. 19-23, 2018.

BioLineRx Discloses Additional Data from Phase 2a COMBAT/KEYNOTE-202 Study in Pancreatic Cancer at ESMO 2018 Congress

20. 10. 18 ladmin

BioLineRx Ltd. (NASDAQ: BLRX) (TASE: BLRX) (TASE: BLRX.TA), a clinical-stage biopharmaceutical company focused on oncology and immunology, today disclosed additional data from the in-depth analyses of biopsies of the dual combination arm of the Phase 2a COMBAT/KEYNOTE-202 study, evaluating patients with metastatic pancreatic adenocarcinoma (PDAC) treated with BL-8040 in combination with KEYTRUDA® (pembrolizumab), an anti-PD-1 therapy marketed by Merck & Co., Inc., Kenilworth, N.J., USA (known as MSD outside of the United States and Canada).

Switchable CAR T Cells May Be Safer in Pancreatic Cancer

19. 10. 18 ladmin

Switchable chimeric antigen receptor (CAR) T cells with a switch directed towards human epidermal growth factor receptor 2 (HER2) in pancreatic ductal adenocarcinoma (PDAC) has similar efficacy as conventional HER2 CAR T cells while also having a greater control over treatment toxicities.

PDAC is the fourth leading cause of cancer-related deaths, with less than 20% of patients having resectable tumors. While CAR T-cell treatments have shown substantial efficacy in hematological malignancies, outcomes in solid tumors such as pancreatic cancer have been limited.

Killer cell immunotherapy offers potential cure for advanced pancreatic cancer

10. 10. 18 ladmin

A new approach to treating pancreatic cancer using ‘educated killer cells’ has shown promise, according to early research by Queen Mary University of London.

The new cell-based immunotherapy, which has not yet been tested in humans with pancreatic cancer, led to mice being completely cancer-free, including cancer cells that had already spread to the liver and lungs.

Cancer stem cells use “normal” genes in abnormal ways

10. 10. 18 ladmin

CDK1 is a “normal” protein – its presence drives cells through the cycle of replication. And MHC Class I molecules are “normal” as well – they present bits of proteins on the surfaces of cells for examination by the immune system. But a University of Colorado Cancer Center study published in the journal Cancer Research shows that a population of cancer cells marked by MHC Class I molecules and high CDK1 is anything but normal.

CDK1 interacts with Sox2 and promotes tumor initiation in human melanoma

8. 10. 18 ladmin

Cancers are comprised of heterogeneous subpopulations with various tumor-initiating capacities, yet key stem cell genes associated with enhanced tumor initiating capacities and their regulatory mechanisms remain elusive. Here we analyzed patient-derived xenografts from melanoma, colon, and pancreatic cancer tissues and identified enrichment of tumor-initiating cells in MHC class I-hi cells, where CDK1, a master regulator of the cell cycle, was upregulated.

Doctors hail new approach in pancreatic cancer treatment

21. 9. 18 ladmin

A new treatment that kills two genes responsible for causing pancreatic cancer — one of the most fatal forms of the disease — is being hailed as a possible breakthrough.

Dr. James Cleary, an oncologist at the Dana-Farber Cancer Institute in Boston, said pancreatic cancer research had been “left behind” — but not anymore.

Universal genetic testing feasible at time of pancreatic cancer diagnosis

31. 8. 18 ladmin

The prevalence of pathogenic germline variants associated with pancreatic ductal adenocarcinoma and limitations of current methods to determine testing eligibility may warrant universal germline genetic testing at the time of diagnosis, according to a study of a consecutive cohort.

Full genetic testing may identify actionable genetic mutations among patients who would not have been tested under current guidelines, and also may identify future cancer risks for family members.

Pancreatic cancer: Mutable cancer cells are more dangerous

7. 8. 18 ladmin

Pancreatic cancer often spreads, forming metastases in the liver or lungs. The prognosis is better for patients with metastases in the lungs. However, the organ that is more likely to be affected depends on the cancer cells’ ability to alter their characteristics and shape – as a research team at the Technical University of Munich (TUM) has discovered.